In a few paragraphs I need to detail the pathophysiology of type 2 diabetes

● This section will detail the pathophysiology of T2D, with an emphasis on glucose dysregulation and its impact.

● A link to sedentary activity will be emphasized, and how glucose regulation can be accomplished with physical activity.

● The dietary pathophysiology will also be expounded upon.

● The above will be discussed in the context of peripheral insulin resistance, impaired hepatic glucose production, and declining beta cell function

Relevant sources:

 Zaccardi F, Webb DR, Yates T, et alPathophysiology of type 1 and type 2 diabetes mellitus: a 90-year perspectivePostgraduate Medical Journal 2016;92:63-69.

 Bergman, M. Pathophysiology of prediabetes and treatment implications for the prevention of type 2 diabetes mellitus. Endocrine 43, 504–513 (2013). https://doi.org/10.1007/s12020-012-9830-9

 Reaven GM. 1998 The role of insulin resistance in human disease. Diabetes. 37:1595–1607.

 Olefsky JM. 1989 Pathogenesis of non-insulin dependent diabetes (type 2). In: DeGroot LJ, Besser GM, Cahill JC, eds. Endocrinology, 2nd ed. Philadelphia: Saunders; 1369–1388.