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How did the expansion of print cultu Question
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</p><b> <p><b> </b></p> <ul><li><b><span class="t286pc" data-sfc-cp="" jscontroller="fly6d" jsuid="s7xg3c_u" data-complete="true"><b>semi-conservative:</b>each new dna molecule =<b>1 old strand</b>(template) +<b>1 new strand</b>.</span><span class="txxdge notranslate" jsaction="rcuq6b:&s7xg3c_y|npt2md" jscontroller="udas2b" data-wiz-uids="s7xg3c_z,s7xg3c_10" data-complete="true"><span class="vkekvd" data-animation-atomic="" data-wiz-attrbind="class=s7xg3c_y/tkhnvd" data-sae=""><span></span><b><span class="wimplc ofc0ud"></span></b></span></span></b></li></ul> <p><b><b></b></b></p><b><b> <p><span class="yjhzub" jscontroller="zymgkd" jsuid="s7xg3c_15" data-complete="true">2. key molecular actors</span><span class="txxdge notranslate" jsaction="rcuq6b:&s7xg3c_16|npt2md" jscontroller="udas2b" data-wiz-uids="s7xg3c_17,s7xg3c_18" data-complete="true"><span class="vkekvd" data-animation-atomic="" data-wiz-attrbind="class=s7xg3c_16/tkhnvd" data-sae=""><span></span><b><span class="wimplc ofc0ud"><br></span></b></span></span></p><p><b> </b></p><b> <ul><li><span class="t286pc" data-sfc-cp="" jscontroller="fly6d" jsuid="s7xg3c_1b" data-complete="true"><b>helicase:</b>"unzips" the double helix (breaks hydrogen bonds).</span></li><li><span class="t286pc" data-sfc-cp="" jscontroller="fly6d" jsuid="s7xg3c_1e" data-complete="true"><b>topoisomerase:</b>prevents "supercoiling" (tension) ahead of the fork.</span></li><li><span class="t286pc" data-sfc-cp="" jscontroller="fly6d" jsuid="s7xg3c_1h" data-complete="true"><b>ssb proteins:</b>hold the strands open (prevent re-zipping).</span></li><li><span XXXXX="XXXXXX" data-XXX-XX="" jscontroller="XXXXX" XXXXX="XXXXXXXXX" XXXX-complete="true"&XX;<b>XXXXXXX:</b>places<b>XXX XXXXXXX</b>(XXX "XXXXX" XXXXXX).</span></li><li><span XXXXX="t286pc" XXXX-XXX-cp="" jscontroller="fly6d" jsuid="s7xg3c_1o" XXXX-complete="true"&XX;<b>dna polymerase XXX:</b>XXX "builder" (adds nucleotides<span XXXXX="mtejhd" XXXXXXXX="rcuq6b:&s7xg3c_1q|npt2md" XXXXXXXXXXXX="XXXXXX" XXXX-complete="true"><span class="XXXXXX"&XX;<img> </span&XX;&XX;/span>).</span&XX;</li><li>&XX;span XXXXX="XXXXXX" XXXX-XXX-XX="" jscontroller="fly6d" jsuid="XXXXXXXXX" XXXX-XXXXXXXX="XXXX"><b>dna polymerase i:</b>the "eraser" (replaces rna XXXXXXX with XXX).</span></li><li><span class="t286pc" data-sfc-XX="" XXXXXXXXXXXX="XXXXX" XXXXX="s7xg3c_1v" data-complete="true"><b>ligase:</b>XXX "XXXX" (XXXXX XXX XXXXXXXXX).&XX;/span><span XXXXX="XXXXXX XXXXXXXXXXX" XXXXXXXX="rcuq6b:&XXX;s7xg3c_1x|npt2md" jscontroller="udas2b" data-wiz-XXXX="s7xg3c_1y,XXXXXXXXX" data-complete="true"&XX;<span class="XXXXXX" XXXX-XXXXXXXXX-atomic="" XXXX-wiz-attrbind="class=XXXXXXXXX/XXXXXX" data-sae=""&XX;<span&XX;</span><b>&XX;span class="wimplc ofc0ud"&XX;&XX;/span&XX;</b>&XX;/span&XX;</span></li></ul> <p><b></b></p><b> <p><span XXXXX="yjhzub" XXXXXXXXXXXX="XXXXXX" jsuid="XXXXXXXXX" XXXX-XXXXXXXX="true">3. the process (step-by-XXXX)</span&XX;&XX;span class="txxdge notranslate" XXXXXXXX="rcuq6b:&XXX;XXXXXXXXX|npt2md" jscontroller="udas2b" XXXX-XXX-XXXX="XXXXXXXXX,XXXXXXXXX" XXXX-complete="true">&XX;span XXXXX="XXXXXX" XXXX-XXXXXXXXX-XXXXXX="" data-XXX-attrbind="class=s7xg3c_25/tkhnvd" data-XXX=""&XX;&XX;span&XX;&XX;/span&XX;<b><span XXXXX="wimplc XXXXXX"&XX;<XX>&XX;/span></b></span></span></p><p><b> <b>i. XXXXXXXXXX</b><span XXXXX="XXXXXX notranslate" jsaction="rcuq6b:&XXX;XXXXXXXXX|XXXXXX" jscontroller="udas2b" XXXX-wiz-XXXX="s7xg3c_2b,XXXXXXXXX" data-XXXXXXXX="true" data-XXXXXXXXX="XXXX"&XX;<span XXXXX="XXXXXX" data-XXXXXXXXX-XXXXXX="" data-XXX-XXXXXXXX="XXXXX=s7xg3c_2a/tkhnvd" data-XXX=""&XX;&XX;span>&XX;/span&XX;<b>&XX;span XXXXX="wimplc ofc0ud"&XX;</span></b></span&XX;</span></b></p><b> <p><b> </b></p> <XX><li><b>&XX;span class="XXXXXX" data-XXX-cp="" XXXXXXXXXXXX="fly6d" XXXXX="s7xg3c_2f" XXXX-XXXXXXXX="true"&XX;XXXXXX at the<b>XXXXXX of XXXXXXXXXXX (ori)</b>.&XX;/span></b></li><li><b>&XX;span class="t286pc" XXXX-XXX-XX="" jscontroller="XXXXX" jsuid="XXXXXXXXX" XXXX-complete="XXXX">helicase opens XXX XXX&XX;span class="mtejhd" jsaction="XXXXXX:&XXX;XXXXXXXXX|npt2md" XXXXXXXXXXXX="XXXXXX" data-complete="true"&XX;<span class="dtet0b"><XXX> </span&XX;</span&XX;<b>XXXXXXXXXXX fork</b>XX formed.</span&XX;</b></li><li><b>&XX;span class="XXXXXX" data-XXX-cp="" XXXXXXXXXXXX="fly6d" jsuid="s7xg3c_2m" data-complete="XXXX">XXXXXXX adds a XXXXX rna XXXXXXXX to XXXX dna XXX iii a XXXXXXXX point.&XX;/span><span class="txxdge XXXXXXXXXXX" jsaction="XXXXXX:&s7xg3c_2n|npt2md" XXXXXXXXXXXX="XXXXXX" XXXX-wiz-uids="s7xg3c_2o,s7xg3c_2p" XXXX-complete="true">&XX;span class="vkekvd" data-animation-atomic="" XXXX-XXX-XXXXXXXX="class=s7xg3c_2n/tkhnvd" data-XXX="">&XX;span>&XX;/span&XX;<b><span XXXXX="wimplc ofc0ud"></span></b></span></span></b></li></ul> <p><b><b><b>ii. XXXXXXXXXX</b><span class="txxdge notranslate" jsaction="rcuq6b:&s7xg3c_2s|npt2md" jscontroller="udas2b" data-XXX-XXXX="s7xg3c_2t,XXXXXXXXX" data-XXXXXXXX="XXXX" data-processed="XXXX"><span class="XXXXXX" data-animation-atomic="" XXXX-wiz-attrbind="XXXXX=s7xg3c_2s/XXXXXX" XXXX-XXX=""><span>&XX;/span&XX;<b><span class="wimplc ofc0ud"&XX;<XX>&XX;/span&XX;</b>&XX;/span></span></b></b></p><p><b><b><b> </b></b></b></p><b><b><b> <XX><li><span XXXXX="t286pc" data-XXX-cp="" XXXXXXXXXXXX="fly6d" XXXXX="XXXXXXXXX" XXXX-complete="XXXX"&XX;<b>leading XXXXXX:</b></span&XX;<XX><li><span XXXXX="XXXXXX" XXXX-sfc-XX="" XXXXXXXXXXXX="XXXXX" jsuid="s7xg3c_31" XXXX-XXXXXXXX="XXXX">XXXXXXXXX:<span class="XXXXXX" jsaction="rcuq6b:&XXX;XXXXXXXXX|npt2md" jscontroller="XXXXXX" XXXX-complete="XXXX"><span class="XXXXXX"&XX;<img> </span>&XX;/span>(XXXXXXX XXX fork).&XX;/span></li><li><span class="t286pc" data-sfc-XX="" jscontroller="XXXXX" jsuid="s7xg3c_34" data-XXXXXXXX="true">synthesis:<b>XXXXXXXXXX</b>.</span&XX;</li></ul></li><li>&XX;span XXXXX="XXXXXX" XXXX-sfc-XX="" XXXXXXXXXXXX="fly6d" XXXXX="XXXXXXXXX" XXXX-XXXXXXXX="XXXX"><b>XXXXXXX strand:</b></span><XX><li>&XX;span class="t286pc" data-sfc-XX="" jscontroller="fly6d" jsuid="XXXXXXXXX" XXXX-XXXXXXXX="true"&XX;direction:&XX;span class="mtejhd" XXXXXXXX="rcuq6b:&XXX;XXXXXXXXX|npt2md" jscontroller="dunije" XXXX-complete="true"><span XXXXX="XXXXXX"><XXX> &XX;/span></span>(away from XXX fork).</span&XX;</li><li><span class="t286pc" XXXX-sfc-cp="" jscontroller="XXXXX" XXXXX="s7xg3c_3e" XXXX-complete="true">XXXXXXXXX:<b>XXXXXXXXXXXXX</b>via<b>okazaki fragments</b>.&XX;/span&XX;</li><li><span class="t286pc" XXXX-XXX-XX="" jscontroller="XXXXX" jsuid="XXXXXXXXX" XXXX-XXXXXXXX="XXXX">XXXXXXX: XXXXXXX<span class="mtejhd" jsaction="rcuq6b:&XXX;s7xg3c_3j|XXXXXX" jscontroller="dunije" data-XXXXXXXX="true">&XX;span class="XXXXXX"><XXX> &XX;/span>&XX;/span&XX;dna XXX iii<span XXXXX="mtejhd" jsaction="XXXXXX:&XXX;s7xg3c_3k|XXXXXX" XXXXXXXXXXXX="dunije" data-complete="XXXX">&XX;span class="dtet0b"&XX;<img> &XX;/span&XX;&XX;/span&XX;XXX XXX i (removes XXXXXX)&XX;span XXXXX="mtejhd" jsaction="XXXXXX:&XXXXXXXXX|npt2md" jscontroller="dunije" XXXX-complete="XXXX"&XX;<span class="dtet0b"&XX;<img> &XX;/span>&XX;/span>ligase.</span&XX;<span XXXXX="txxdge XXXXXXXXXXX" jsaction="XXXXXX:&XXXXXXXXX|npt2md" jscontroller="XXXXXX" XXXX-XXX-uids="s7xg3c_3n,s7xg3c_3o" data-XXXXXXXX="true"><span class="vkekvd" XXXX-animation-atomic="" data-XXX-XXXXXXXX="XXXXX=s7xg3c_3m/XXXXXX"><span>&XX;/span&XX;<b>&XX;span class="XXXXXX XXXXXX"&XX;</span></b>&XX;/span>&XX;/span&XX;</li></ul></li></ul> <p><b><b>XXX. termination</b><span class="XXXXXX XXXXXXXXXXX" jsaction="XXXXXX:&XXX;s7xg3c_3r|npt2md" jscontroller="XXXXXX" XXXX-wiz-uids="s7xg3c_3s,s7xg3c_3t" XXXX-complete="XXXX" XXXX-XXXXXXXXX="XXXX"><span class="vkekvd" data-animation-XXXXXX="" data-wiz-attrbind="XXXXX=XXXXXXXXX/XXXXXX" data-sae=""><span></span&XX;<b><span XXXXX="wimplc XXXXXX"&XX;<XX>&XX;/span&XX;</b></span></span&XX;</b></p><p><b><b> </b></b></p><b><b> <XX><li><span XXXXX="XXXXXX" data-XXX-XX="" jscontroller="fly6d" jsuid="XXXXXXXXX" XXXX-complete="XXXX"&XX;<b>XXXXXXXXXXX:</b>XXX XXXXX meet at a specific "stop" site.</span></li><li><span class="t286pc" XXXX-sfc-cp="" jscontroller="fly6d" jsuid="XXXXXXXXX" XXXX-complete="XXXX"><b>XXXXXXXXXX:</b>occurs at XXX XXXX of linear chromosomes.&XX;/span></li><li><span XXXXX="t286pc" XXXX-XXX-XX="" jscontroller="fly6d" jsuid="s7xg3c_42" XXXX-complete="true"&XX;<em>note:</em><b>XXXXXXXXXX</b>XXXXXXX the XXXX (telomeres) XX XXXXXXX gene XXXX.</span&XX;<span XXXXX="XXXXXX XXXXXXXXXXX" jsaction="XXXXXX:&XXX;XXXXXXXXX|npt2md" jscontroller="XXXXXX" data-XXX-XXXX="XXXXXXXXX,XXXXXXXXX" XXXX-complete="true"&XX;<span class="XXXXXX" XXXX-animation-atomic="" XXXX-wiz-XXXXXXXX="class=XXXXXXXXX/XXXXXX" XXXX-sae="">&XX;span></span&XX;<b>&XX;span class="XXXXXX XXXXXX"&XX;</span></b>&XX;/span>&XX;/span&XX;</li></ul> <p><b></b></p><b> <p>&XX;span class="XXXXXX" jscontroller="XXXXXX" jsuid="XXXXXXXXX" XXXX-XXXXXXXX="XXXX"&XX;X. quality control (accuracy)</span>&XX;span XXXXX="XXXXXX XXXXXXXXXXX" XXXXXXXX="XXXXXX:&XXX;s7xg3c_4d|XXXXXX" jscontroller="udas2b" XXXX-wiz-uids="s7xg3c_4e,s7xg3c_4f" XXXX-complete="true"&XX;&XX;span class="vkekvd" data-animation-XXXXXX="" data-XXX-XXXXXXXX="XXXXX=XXXXXXXXX/XXXXXX" data-sae="">&XX;span>&XX;/span><b><span class="wimplc XXXXXX"&XX;<XX></span&XX;</b>&XX;/span&XX;</span></p><p><b> </b></p><b> <ol&XX;<li><span XXXXX="XXXXXX" XXXX-XXX-cp="" XXXXXXXXXXXX="fly6d" XXXXX="s7xg3c_4i" XXXX-complete="XXXX"&XX;<b>XXXXXXXXXXXX:</b>XXX polymerase XXXXXX its own work; if it XXXXX a mistake, it goes back XXX XXXXX it immediately (<span XXXXX="XXXXXX" XXXXXXXX="rcuq6b:&XXX;XXXXXXXXX|XXXXXX" XXXXXXXXXXXX="XXXXXX" XXXX-complete="true"&XX;&XX;span class="XXXXXX"><img> &XX;/span&XX;&XX;/span>exonuclease XXXXXXXX).&XX;/span&XX;</li><li><span class="XXXXXX" XXXX-XXX-XX="" XXXXXXXXXXXX="fly6d" XXXXX="XXXXXXXXX" data-complete="XXXX"><b>XXXXXXXX XXXXXX (mmr):</b>proteins XXXX XXX XXX<em>XXXXX</em>synthesis XX swap out XXX mismatched XXXX pairs that XXXXXXX XXXXXXXXXXXX.</span><span XXXXX="txxdge notranslate" jsaction="XXXXXX:&XXXXXXXXX|XXXXXX" jscontroller="udas2b" XXXX-XXX-XXXX="XXXXXXXXX,s7xg3c_4r" data-complete="XXXX"><span XXXXX="XXXXXX" XXXX-animation-XXXXXX="" XXXX-wiz-XXXXXXXX="XXXXX=XXXXXXXXX/XXXXXX" XXXX-XXX="">&XX;span&XX;</span><b><span XXXXX="wimplc ofc0ud"&XX;&XX;/span&XX;</b>&XX;/span></span></li>&XX;/ol&XX; <p><b></b></p><b> <p>&XX;span XXXXX="yjhzub" jscontroller="XXXXXX" jsuid="s7xg3c_4w" data-complete="XXXX"&XX;5. comparison: prokaryotes vs. XXXXXXXXXX&XX;/span&XX;&XX;span class="XXXXXX notranslate" jsaction="rcuq6b:&XXX;s7xg3c_4x|XXXXXX" XXXXXXXXXXXX="XXXXXX" XXXX-XXX-uids="XXXXXXXXX,XXXXXXXXX" data-XXXXXXXX="true">&XX;span class="XXXXXX" data-XXXXXXXXX-atomic="" XXXX-wiz-attrbind="class=XXXXXXXXX/tkhnvd" data-XXX=""><span&XX;&XX;/span><b><span class="XXXXXX XXXXXX"&XX;<XX>&XX;/span></b>&XX;/span&XX;</span></p><p><b> </b></p><b> <table><tbody><tr><th>feature&XX;span class="txxdge notranslate" XXXXXXXX="XXXXXX:&s7xg3c_54|npt2md" XXXXXXXXXXXX="udas2b" data-XXX-XXXX="s7xg3c_55,s7xg3c_56" data-XXXXXXXX="XXXX"&XX;&XX;span XXXXX="vkekvd" data-XXXXXXXXX-atomic="" data-wiz-XXXXXXXX="class=XXXXXXXXX/XXXXXX" XXXX-XXX=""&XX;<span&XX;&XX;/span><b><span XXXXX="wimplc XXXXXX"></span&XX;</b>&XX;/span></span&XX;</th><th>prokaryotes</th><th>XXXXXXXXXX</th></tr><tr><td><b>dna shape</b></td><td>circular</td><td>XXXXXX</td></tr><tr><td><b>XXXXXXX</b></td><td>single (XXX "ori")</td><td>XXXXXXXX (XXXXXXXXX)</td></tr><tr><td><b>XXXXX</b></td><td>XXXX XXXX</td><td>XXXXXX</td></tr><tr><td><b>XXXXXXXX</b></td><td>XXXXXXXXX</td><td>nucleus</td></tr></tbody></table> </b></b></b></b></b></b></b></b></b></b></b></b></b></b></b><p><b><b><b><b><b><b><b><b><b><b><b><b><b><b><b></b></b></b></b></b></b></b></b></b></b></b></b></b></b></b></p>">
