Diet and mood. Researchers were interested in comparing the long-term psychological effects of being on a high-carbohydrate, low-fat (LF) diet versus a high-fat, low-carbohydrate (LC) diet. A total of 106 overweight and obese participants were randomly assigned to one of these two energy-restricted diets. At 52 weeks, 32 LC dieters and 33 LF dieters remained. Mood was assessed using a total mood disturbance score (TMDS).